Journal of Regional Section of Serbian Medical Association in Zajecar

Year 2004     Volumen 29     Number 3
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  UDK 615.222.06:616.441 ISSN 0350-2899, 29(2004) 3 p.205-209
Case Report

Amiodarone Induced Thyrotoxicosis (AIT) Type 2
Several Months After Withdrawal of Amiodarone Therapy

Željka Aleksić, Aleksandar Aleksić
Nuclear Medicine, Medical Centre Zajecar



We report a case of a male patient on chronic amiodarone (AMD) treatment who developed altered thyroid dysfunction. Nine months after initiation of the AMD therapy he developed distinct biochemical signs of hypothyroidism, which spontaneously resolved after the withdrawal of AMD. AMD was administered again after one year due to refractory arrhythmia. After 3 years AMD was ceased when elevated serum TSH was registered. Eight months after withdrawal, worsening of arrhythmia occurs, serum levels of functional thyroid parametars show hyperthyroidism, scintigraficly thyroid was »blocked«, and semiqantitative uroiodine test reveals increased levels of iodine in urine. We presumed findings as amiodarone induced thyrotoxicosis (AIT) type 2, and the results have normalised during the glucocorticoid therapy. Currently, patient is eumetabolic with no therapy.

Key words: Amiodarone, amiodarone induced thyrotoxicosis (AIT) type 2

Napomena: kompletan tekst rada na srpskom jeziku
Note: full text in Serbian
  Corresponding Address:
Željka Aleksić
Zdravstveni centar Zaječar, Služba za nuklearnu medicinu
Rasadnička B.B, 19000 Zaječar,
e-mail: lukaal@ptt.yu
  Paper received: 10. 08. 2004.
Paper accepted: 26. 08. 2004.
Published online: 18. 09. 2004.
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